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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
38.18
Human Site:
S188
Identified Species:
60
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S188
P
T
R
E
Q
L
D
S
G
R
I
G
A
D
E
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S303
P
T
R
E
Q
L
D
S
G
R
I
G
A
D
E
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S188
P
T
R
E
Q
L
D
S
G
R
I
G
A
D
E
Dog
Lupus familis
XP_541147
492
57155
S188
P
T
R
E
Q
L
D
S
G
R
I
G
A
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S188
P
T
K
E
Q
L
D
S
G
R
I
G
A
D
E
Rat
Rattus norvegicus
NP_001101927
357
40656
V97
K
K
G
T
V
S
M
V
N
N
G
S
D
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
S184
P
T
K
E
Q
L
N
S
G
R
I
G
A
D
E
Chicken
Gallus gallus
XP_419663
478
55881
S188
P
T
K
E
Q
L
D
S
G
R
I
G
A
D
E
Frog
Xenopus laevis
Q6GLX7
477
54856
N202
A
K
G
T
K
N
F
N
L
L
S
F
G
E
E
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
S188
P
T
K
Q
Q
L
D
S
G
R
I
G
A
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
N188
P
S
A
E
R
L
K
N
G
R
I
A
A
D
E
Honey Bee
Apis mellifera
XP_001121334
512
60307
S188
P
T
K
E
V
L
M
S
D
R
I
G
A
D
E
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
D167
I
V
L
D
D
P
F
D
E
D
A
R
I
S
F
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
Q181
E
D
D
D
G
K
T
Q
E
E
L
E
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
T199
P
S
K
A
Q
L
A
T
V
R
I
T
E
G
E
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
86.6
93.3
6.6
86.6
N.A.
60
73.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
100
26.6
100
N.A.
80
80
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
7
0
0
0
7
7
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
14
7
0
47
7
7
7
0
0
7
67
0
% D
% Glu:
7
0
0
60
0
0
0
0
14
7
0
7
7
14
87
% E
% Phe:
0
0
0
0
0
0
14
0
0
0
0
7
0
0
7
% F
% Gly:
0
0
14
0
7
0
0
0
60
0
7
60
14
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
74
0
7
0
0
% I
% Lys:
7
14
40
0
7
7
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
74
0
0
7
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
14
7
7
0
0
0
0
0
% N
% Pro:
74
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
60
0
0
7
0
0
0
0
0
7
0
% Q
% Arg:
0
0
27
0
7
0
0
0
0
74
0
7
0
0
0
% R
% Ser:
0
14
0
0
0
7
0
60
0
0
7
7
0
7
0
% S
% Thr:
0
60
0
14
0
0
7
7
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
14
0
0
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _